stall on tirzepatide Weight Loss Plateau: 9 Reasons Progress Slows Stop guessing. If fat loss

Phase 2: Published in the New England Journal of Medicine

& Jain, S

It's best to see a doctor if: A good dermatologist will always screen you before beginning treatment

Common Side Effects Dry persistent cough Hypotension Dizziness Hyperkalemia Taste disturbance (metallic taste) Serious Adverse Effects Angioedema (life-threatening) Severe hyperkalemia Acute kidney injury Neutropenia (rare) Contraindications Pregnancy (teratogenic) Bilateral renal artery stenosis History of ACE inhibitor-induced angioedema Drug Interactions Avoid combination with: Potassium supplements Potassium-sparing diuretics (spironolactone) NSAIDs (reduce effect + kidney risk) Other antihypertensives (risk of hypotension) Monitoring Parameters Blood pressure Serum potassium Serum creatinine Renal function Counseling Points Take 1 hour before meals (better absorption) Do not stop suddenly Report swelling of face/lips immediately Avoid potassium-rich salt substitutes Dry cough is common Clinical Pearls First ACE inhibitor developed Short-acting requires multiple daily dosing If patient develops cough switch to ARB (like Losartan) Useful in diabetic patients for kidney protection Summary Captopril is a short-acting ACE inhibitor effective for hypertension and heart failure but requires careful monitoring due to risks of cough, hyperkalemia, and angioedema